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Janaury 31 , 2003

Western Elk, Deer are Dying of Brain Disease

By Patrick O'Driscoll USA TODAY

DENVER -- Although mad cow disease has yet to show up in America, a similar disorder exists in some herds of wild and captive deer and elk here in the West.

Chronic wasting disease (CWD) does not appear to transfer to cattle or to humans -- at least, not easily. So far, researchers have been able to infect cattle only by injecting the brains of test animals with the protein molecules, or prions, that trigger the affliction.

CWD, first noted in the late '60s, attacks the brain and is always fatal, just like its infamous cattle-killing cousin, bovine spongiform encephalopathy, better known as mad cow disease.

CWD-infected wildlife, mostly mule deer, have been found in pockets of northeastern Colorado, southeastern Wyoming and western Nebraska. The disease also has struck some elk on game farms in South Dakota, Nebraska, Montana, Colorado, Oklahoma and the Canadian province of Saskatchewan.

This month, Colorado wildlife officials said that testing of deer shot by hunters around the state confirms that the disorder hasn't spread. But Tom Thorne, wildlife veterinarian for the Wyoming Game and Fish Department, says, ''There is every reason to expect that, over time, (the range) will expand.''

Colorado is trying to reduce CWD's occurrence in its most disease-infested game management area by holding a special deer hunt from December through February this season and again in 2002 and 2003.

As many as 15% of deer killed in that zone north of Fort Collins in previous seasons tested positive for chronic wasting. Biologists think that reducing the density of the wild herd may slow the disease's spread.

Thorne bristles at popular media descriptions of CWD as ''mad deer'' disease. Given the behavior of animals afflicted with it, ''they ought to call it 'sleepy deer' or 'slobbery deer,' '' he says. CWD causes animals to lose weight and conditioning, eventually leading to death.

Nor is Thorne alarmed about an epidemic, saying it is highly unlikely the malady can spread to humans, whether by eating venison or through other contact. He says a recent study at the National Institutes of Health's Rocky Mountain Laboratory in Montana came to the same conclusion.

But given how little is yet known about CWD, state wildlife agencies are cautioning hunters to wear rubber gloves when field-dressing deer carcasses and to avoid handling brain or spinal tissues, which are thought to harbor the disease pathogens.

''Now, you can never say 'never,' but I have probably been exposed to this disease over a longer period of time than almost anybody,'' says Thorne, who has studied chronic wasting for more than three decades. ''I guess if there's an ongoing experiment, it's me.'' In fact, he jokes, ''I'm certain that if I die of (CWD), I will be written up extensively.''

His wife, Elizabeth Williams, is a leading CWD researcher at the state lab at the University of Wyoming. She has autopsied and handled ''more material than anybody,'' Thorne says. In addition, he and his wife regularly hunt and consume venison at their hunting cabin in the Laramie Peak area, where Wyoming's largest concentration of infected deer is found.

''We're the experiment, and we're not worried,'' Thorne says. ''Now, I wouldn't inject it into my brain, but beyond that, we're really not concerned.''


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